细胞间相互作用分析发现,接受化疗的 CLDN18.2 阳性胃癌存在独特的相互作用,包括细胞毒性 NK 细胞(信号发送者)与效应 Tregs(信号接收者)之间的 CCL5 - CCR5 信号传导,以及效应 Tregs(信号发送者)与 TAMs(信号接收者)之间的 TGFB1 - TGFBR 信号传导。与未接受 ...
We performed single-cell RNA sequencing on 11 samples of ADC tumor tissues, with other 4 SCC samples served as controls. The immunochemistry and multiplexed immunofluorescence were conducted to ...
Department of Medicine, Section of Pulmonary and Critical Care Medicine, The University of Chicago, Chicago, IL, United States Immunometabolism has emerged as a key area of focus in immunology and has ...
Background: Lung adenocarcinoma (LUAD) is one of the most common malignant tumors globally, characterized by poor prognosis and high mortality. Abnormal fatty acid metabolism plays a crucial role in ...