Workers' Liberty5 天Opinion
Unison: vote TFRC and build the grassroots!
Public service union Unison boasts of being the UK’s biggest union with 1.3m members, but so far size has been no indication ...
IEEE6 天
End-to-end Congestion Control for TCP-friendly Flows with Variable Data Rates
Abstract: This paper presents recent new findings on the network resource utilization bias phenomenon in the context of TCP-friendly rate control (TFRC) protocol based data flows. It has been found ...
EMBO Press3 天
TFE3 fusions drive oxidative metabolism and ferroptosis resistance in translocation renal ...
TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...
生物通5 天
综述：铁死亡的新兴机制洞察—癌症治疗的新调节剂
RSV 可通过增加细胞内 ROS、MDA 和 Fe 2+ 积累，下调 SLC7A11，诱导铁死亡，抑制肿瘤生长；在实体腺癌中，通过降低 GPX4 和 SLC7A11 的表达，增加 TFRC 和 ACSL4 的表达，增强 CD8 + T 细胞的细胞毒性，触发铁死亡，实现抗肿瘤目标；此外，RSV 还可抑制促炎细胞因子水平 ...