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HEK293T and TZM-bl cells were cultured in DMEM (ThermoFisher, 11965092) supplemented with Penicillin/Streptomycin and 10% FBS. All cells were maintained at 37ºC with 5% CO2. The HuEpi screen was ...
虽然抑制剂的剂量依赖性细胞膜锚定不影响 CCR5 受体表达水平,但 TZM-bl 细胞上的表达水平可能远高于体内主要靶细胞 —— 初级 CD4 + T 细胞上的表达水平。此外,研究人员还关注能否将 2P23 肽直接连接到 PRO 140 的原型抗体上,在保持基于 scFv 的融合蛋白抗病毒 ...
The persistence of latent HIV reservoirs allows for viral rebound upon antiretroviral therapy interruption, hindering effective HIV-1 cure. Emerging evidence suggests that modulation of innate immune ...
这篇研究聚焦 HIV-1 包膜糖蛋白(Env)。CRF01_AE 毒株的 Env 在 375 位有组氨酸(H375),影响对小分子抑制剂的抗性。研究发现 gp41 HR2 区 629 位残基可调节 Env 稳定性及对两类小分子 gp120 抑制剂的敏感性,为理解 HIV-1 Env 耐药机制提供新视角。 引言 HIV-1 包膜糖蛋白 ...
观点网讯:3月5日,全国人大代表、小米集团董事长雷军表示,作为民营企业家,听完政府工作报告后,我觉得万事ok!对中国经济的前景,充满了 ...
Zenless Zone Zero codes are one of the best ways to get free Polychrome for pulling new characters in miHoYo's latest action game. Sure, you'll get plenty by playing the game at launch, but it'll ...
Navigation apps have become necessary for those on the move, offering precise maps and real-time traffic updates for efficient travel. These apps, powered by GPS technology, share standard ...
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