HEK293T and TZM-bl cells were cultured in DMEM (ThermoFisher, 11965092) supplemented with Penicillin/Streptomycin and 10% FBS. All cells were maintained at 37ºC with 5% CO2. The HuEpi screen was ...

虽然抑制剂的剂量依赖性细胞膜锚定不影响 CCR5 受体表达水平，但 TZM-bl 细胞上的表达水平可能远高于体内主要靶细胞 —— 初级 CD4 + T 细胞上的表达水平。此外，研究人员还关注能否将 2P23 肽直接连接到 PRO 140 的原型抗体上，在保持基于 scFv 的融合蛋白抗病毒 ...

这篇研究聚焦 HIV-1 包膜糖蛋白（Env）。CRF01_AE 毒株的 Env 在 375 位有组氨酸（H375），影响对小分子抑制剂的抗性。研究发现 gp41 HR2 区 629 位残基可调节 Env 稳定性及对两类小分子 gp120 抑制剂的敏感性，为理解 HIV-1 Env 耐药机制提供新视角。 引言 HIV-1 包膜糖蛋白 ...

Navigation apps have become necessary for those on the move, offering precise maps and real-time traffic updates for efficient travel. These apps, powered by GPS technology, share standard ...

Dermatologists are here to help with that last issue. A key trick to finding the cause of acne, they said, is noting where the breakout is located on your face — it’s called facial mapping. This ...

Teledyne FLIR OEM, part of Teledyne Technologies Incorporated, announced that Sentera Sensors and Drones, a pioneering provider of advanced sensors and data, has joined the Thermal by FLIR program.