为探究 TCF7L2 rs7903146 基因型与饮食对心血管疾病风险影响，研究发现地中海饮食对 TT 基因型者有益。 在健康与疾病的探索中，心血管疾病（CVD）始终是全球关注的焦点。转录因子 7 样 2（TCF7L2）基因与代谢和心血管疾病风险紧密相关，其 rs7903146 位点的变异备受 ...

Type 2 diabetes can be inherited, but environmental factors also play a role. Not everyone with a family history of type 2 diabetes will get it, but you’re more likely to develop it if a parent ...

Gestational diabetes is a major public health problem because of its prevalence, its associated complications during pregnancy, and its increased risk for type 2 diabetes later in life. Insulin ...

Objective: To construct an immune-related gene prognostic index (IRGPI) for breast cancer (BC) and investigate its prognostic specificity and the molecular and immune characteristics. Methods: BC hub ...

Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) could offer a treatment option for kidney transplant recipients with type 2 diabetes (T2D) because the medications were found to be linked to ...

Berberine ursodeoxycholate (HTD1801) showed potential as a treatment option for patients with type 2 diabetes (T2D), with significant reductions in A1c and fasting plasma glucose levels. The ...

然而，随着研究的深入，科学家们发现，传统认知下的神经元类型远远不能涵盖 SC 的复杂性。单细胞转录组学技术的出现，如同给科学家们配备了一台 “超级显微镜”，让他们得以窥见更丰富的神经元亚型。研究人员通过单细胞核 RNA 测序（snRNA-seq），将 sSC 神经元细分为 28 个转录组簇，包括 10 个兴奋性和 18 个抑制性簇，这一发现为深入探究 SC ...

有研究发现，2型糖尿病相关的基因有上百种，其中最有名的就是TCF7L2基因，这个基因的突变会影响胰岛素的分泌，让血糖更容易失控。 更麻烦的是，这种遗传并不是一出生就表现出来，而是随着年龄增长，胰岛功能逐渐下降，再加上饮食和生活习惯的影响 ...

Osteoarthritis (OA) is the most common degenerative joint disease worldwide, characterized by synovial inflammation, cartilage loss, and reactive hyperplasia of subchondral bone, affecting the quality ...

Impact of Insurance Status on Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma This retrospective analysis included patients with cancer who had commercial ctDNA tests (K-Track, Gene ...

那些总在控糖路上碰壁的人，可能忽视了个体差异的密码。基因检测发现，携带TCF7L2基因变异者，对膳食纤维的血糖调节反应比常人强3倍；而SLC2A2基因突变人群，更适合通过抗阻运动而非饮食控糖。 下次测血糖前，不妨先观察晨起唾液——如果黏稠拉丝 ...