Centromere defects, chromosome instability, and concomitant cGAS-STING pathway activation correlate with increased fibrosis markers, suggesting that the cGAS-STING pathway is linked to immune ...

State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China ...

The objective of this study presented at EAU 2024 was to compare radiographic progression-free survival, overall survival, and treatment-emergent adverse events among mCRPC patients receiving ...

Tumor immune evasion mechanisms could be reversed by activating intracellular antiviral immune responses. It has been reported that the use of DNA methyltransferase (DNMT) inhibitors combined with ...

Deregulation of this pathway is a common event in breast cancer including hormone receptor-positive (HR+) disease, HER2-amplified, and triple negative tumors. Hence, targeting AKT represents an ...

Sting from a scorpion Onset of local pain and tingling after a scorpion is seen in the area The main symptoms are pain, tingling and numbness at the sting site About 85% cause only local symptoms at ...

We studied the role of the cGAS–STING pathway in the IFN-I-producing cascade driven by SLE serum. Methods We collected sera from patients with SLE (n=64), patients with other autoimmune diseases (n=31 ...

Sting is calling out sick. The Grammy-winning British singer-songwriter, 73, has been forced to postpone several upcoming concerts after contracting a throat infection, Sting revealed on social ...

Sting has postponed multiple concerts due to a temporary throat infection. On Tuesday, the veteran musician’s team took to social media to announce the postponement, along with rescheduling ...

Patients who were taking lipid-lowering medications experienced more severe anaphylaxis after insect stings, according to an ...