ABSTRAC: Fibroblasts from the original sialuria patientare shown to contain high levels of free sialic acid, i.e., anaverage of 87 versus a normal average of 2 nmol/mg ofprotein. Gas liquid ...

Reduced sialic acid levels help anemonefish avoid stings from their sea anemone hosts. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

Muscle biopsy shows atrophic fibers and rimmed vacuoles without inflammation. Inherited in an autosomal recessive manner, patients with GNE myopathy carry mutations in the GNE gene which affect the ...

The approach was applied to the sialic acid metabolic pathway in human cells, yielding novel mutants with phenotypes related to the inborn metabolic defect sialuria and metastatic tumor cells.

2008). Within mammalian systems, Chinese hamster ovary (CHO) cells are by far the most common production host (Walsh, 2018; Nguyen et al., 2020); even though they are naturally not able to link sialic ...

School of Materials Science and Engineering, Jiangsu Collaboration Innovation Center of Photovoltaic Science and Engineering, Jiangsu Engineering Laboratory of Light-Electricity-Heat Energy-Converting ...

Uric acid is a waste product found in urine. If your body makes too much or doesn't eliminate enough of it, uric acid levels can become too high—a condition known as hyperuricemia. High uric acid ...

Dietary measures and medications may help reduce uric acid and manage gout. Gout can occur when blood uric acid levels are too high, causing crystals to form in the toes, feet, and other joints.

This valuable work provides novel insights into the substrate binding mechanism of a tripartite ATP-independent periplasmic (TRAP) transporter, which may be helpful for the development of specific ...

Fig1Y onwards is now discussed in the manuscript. In addition, we labelled the surface of living HEK293 cells with wheat germ agglutinin (WGA), which binds to sialic acid and N-acetyl-D-glucosamine.

Malic acid benefits can include acne treatment, and skin care such as exfoliation and hydration. It is an alpha hydroxy acid, found naturally in fruits and wines and used as an ingredient in ...