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综述:猪流行性腹泻病毒宿主限制因子的简要综述
随着更多宿主限制因子的发现,它们为抗 PEDV 药物研发提供了潜在靶点。然而,病毒也进化出多种策略对抗宿主限制因子的作用,如 PEDV 的 Nsp10 降低 SAP18 表达并诱导其细胞质积累,E 蛋白诱导应激颗粒形成抑制宿主细胞蛋白合成。因此,如何激活宿主限制因子的 ...
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