Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with a human mortality rate of up to 30%, posing a significant threat to public health. However, the lack of suitable ...

前言：发热伴血小板减少综合征（severe fever with thrombocytopenia syndrome，SFTS）是由发热伴血小板减少综合征布尼亚病毒（Severe fever withthrombocytopenia syndrome ...

会议伊始，医务科副科长余海燕指出，“发热伴血小板减少综合征（SFTS）”是重要公共卫生议题。自2004年华东地区首次报告病例以来，SFTS的病原学研究与防控策略不断深化。尤其是在2023年，安徽省报告病例数量较高，滁州市及全椒县防控形势尤为严峻，在此 ...

Background: Severe Fever with Thrombocytopenia Syndrome (SFTS) is a disease caused by infection with the Severe Fever with Thrombocytopenia Syndrome virus (SFTSV), a novel Bunyavirus. Accurate ...

SARS-CoV-2 and SFTSV. Protein nanocages are multimeric molecular structures that can be engineered to mimic conformations of microorganisms. Here the authors display antigen and adjuvant on ...

Pattern recognition receptors (PRRs) are expressed by cells in the body in order to sense molecules that are associated with infection or tissue damage. They are important for activating the ...

在流行病学调查方面，对确诊患者及密切接触者进行详细的信息收集，了解他们的接触史、症状出现时间等；通过回顾性队列研究，分析潜在的传播危险因素；还对患者的血液样本进行了 SFTS 病毒（SFTSV）RNA 检测 ，以此确定感染情况。此外，利用基因测序和系统 ...

Northeastern China has a high incidence of tick-borne diseases. Emerging and re-emerging tick-borne viral diseases pose a considerable threat to public health. To date, ten tick-borne viruses have ...

而且，KE-VAC（sM2HA2）能诱导长期的免疫反应，接种 6 个月后仍能有效保护小鼠免受 H1N1 感染。在雪貂模型中，KE-VAC 用于严重发热伴血小板减少综合征病毒（SFTSV）疫苗的实验。结果显示，KE-VAC 能诱导雪貂产生强大的长期中和抗体活性和抗原特异性 T 细胞反应 ...