The second group, constituted by ADM2, TRIB3, CHAC1 and SESN2, is involved in the unfolded protein response (UPR) and finally the third group contains KIF20A, RAD54L and ESPL1, which are involved in ...

This includes PALB2, RAD51B, RAD51C, RAD51D, RAD54L, and BRIP1 (none of these genes have EMA approval). Switching to PARP inhibitor combination therapy, there is preclinical rationale for a combined ...