为探究心肌细胞胞吐及心房利钠肽（ANP）分泌机制，研究人员聚焦 Rab3a GTP 酶循环，发现 G α q 信号及 Rab3a 调节通路促进 ANP 释放，为心血管疾病治疗提供新方向。 在心血管系统的 “舞台” 上，心肌细胞分泌的心房利钠肽（Atrial Natriuretic Peptide，ANP）是一位关键 ...

Zerial, personal communication). Rabphilin, a Rab3A effector, interacts with the actin-bundling protein α-actinin in the absence of Rab3A-GTP76. This may provide a means for Rab3A-GTP to modulate ...

This is an important study that describes the development of optical biosensors for various Rab GTPases and explores the contributions of Rab10 and Rab4 to structural and functional plasticity at ...