Novel technology enables discovery, which could help predict tumour recurrence Researchers from the Fred Hutch Cancer Centre, ...

We found that INTS12 is present on chromatin at the promoter of HIV and therefore its effect on HIV may be direct. Additionally, we observed more RNAPII in the gene body of HIV only with the ...

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In recent years, the influenza viruses have posed an increasingly severe threat to public health. It is essential to analyze the virulence and pathogenesis of influenza viruses to prevent and control ...

RNAPII 的 CTD 区域集中在液体凝聚物中，其降解会导致特定基因座 cohesin 缺失和部分 EP 环消失，同时增强 CTCF 介导的环。虽然目前方法难以区分 TF 耗尽的直接和间接影响，但 RNAPII - AID 等技术表明，RNAPII 可能是通过相分离形成的更大蛋白复合物的一部分，与 cohesin ...

Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia The cytoskeleton plays a crucial role in regulating ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...