RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...

Their study, which was published in Nature Chemical Biology, paves the way for new therapies that can "unfreeze" these RNA structures to combat other mosquito-borne RNA viruses.

Recombinase efficiency increases allow Qi Biodesign ... of the nuclease to go to the right place in the genome due to a RNA guide, and the activity of the transposase to insert large pieces ...

The Ohio State University, Columbus, Ohio 43210, United States Ohio State Biochemistry Graduate Program, The Ohio State University, Columbus, Ohio 43210, United States Biophysics Graduate Program, The ...

Their replication systems blur traditional evolutionary boundaries and serve as living models of early cellular life. Figure 1. Schematic representation of the tree of life showing the distribution of ...

Introduction: Metabolic flexibility is the ability of a system to switch between metabolic substrates. Human and murine skeletal muscle tissues and cells with decreased activity of the regulatory ...

Objective Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular carcinoma (HCC). Conclusion Our ...

To further enhance detection sensitivity and avoid the necessity for sophisticated and costly equipment, nucleic acids-based preamplification techniques, including thermal-dependent amplification, ...