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7 天
综述:猪流行性腹泻病毒宿主限制因子的简要综述
此外,死亡结构域相关蛋白(DAXX)激活 IFN-λ 3-STAT1 信号通路,上调 ISG15 表达,抑制 PEDV 复制;STAT3 通常抑制 IFN-I 抗病毒活性,利于病毒感染,但 PEDV 感染时,非受体酪氨酸磷酸酶 PTPN14 可抑制 STAT3 磷酸化和激活,增强 IFN-I 通路;肿瘤抑制基因 p53 在多种应激 ...
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