However, several weaknesses were noted surrounding the main claims where the supporting data are incomplete. PKC - Notch1 activation: (1) Does deletion of Prkce and Prkch affect blood flow, and if so, ...

These EVs promote the expression of RUNX2 and HDAC6, as well as the expression of long-noncoding RNAs such as lncRNA PVT1 and circ-PRKCH, and inhibit the expression of miRNAs such as miR-93-5p and miR ...

Notch1 is expressed uniformly throughout the mouse endocardium during the initial stages of heart valve formation, yet it remains unclear how Notch signaling is activated specifically in the AVC ...

Osteoarthritis (OA) is a debilitating disease that predominantly impacts the hip, hand, and knee joints. Its pathology is defined by the progressive degradation of articular cartilage, formation of ...