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Wnt信号通路基因变异与老年人血脂及认知功能的关联研究:从分子 ...
来自山东青岛的研究团队针对Wnt信号通路基因变异与轻度认知障碍(MCI)的关联机制展开研究,通过分析459名老年人数据发现PRKCA-rs2286674等SNP与MCI显著相关,首次揭示血脂对PRS(多基因风险评分)效应的修饰作用,并构建随机森林预测模型,为阿尔茨海默病早期 ...
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