Conclusion: GR activation may suppress the Th2 immune response triggered by egg antigens by downregulating the expression of the key transcription factors Gata3 and Pparg. While these findings provide ...

进一步研究表明，NAT10 通过对 Krüppel 样因子 9（KLF9）mRNA 进行 ac 4 C 修饰，增强了 KLF9 mRNA 的稳定性，进而激活了 CCAAT 增强子结合蛋白 α/β- 过氧化物酶体增殖物激活受体 γ（CEBPA/B-PPARG）通路，促进了脂肪生成。此外，研究还发现，特异性 NAT10 抑制剂 Remodelin ...

The PPGBioPred webserver in the prediction of bioactivities for various lead chemical compounds against the targets PPARG. The requirements.txt contains the list of ...

To address this, researchers developed uPEn, integrating a ubiquitin variant (i53) to enhance genome stability and repair efficiency. The study applied uPEn to insert a consensus Kozak sequence into ...

Furthermore, recent genetic studies have demonstrated an association between a known coding SNP in the PPARG gene and psoriatic [2] or rheumatoid arthritis [3]. In recent clinical studies, a PPARγ ...

CAPE CANAVERAL, Fla. — Stuck in space no more, NASA astronauts Butch Wilmore and Suni Williams returned to Earth on Tuesday, ...

Cirius Therapeutics, Inc., developing innovative therapies for patients suffering with diseases caused by insulin resistance, including obesity/overweight and type 2 diabetes (T2D), today announced ...

Reply to the Letter to the Editor: Cemented or Uncemented Hemiarthroplasty for Femoral Neck Fracture? Data from the Norwegian Hip Fracture Register.