In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...
Pathway analyses of DEGs identified by RNA-seq ... RNA-seq and survival data are derived from the TCGA CESC cancer patients. (J/K) AKT and ERK phosphorylation is partially regulated by MCAM and IGFBP3 ...
Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...
The changes in phosphorylation states of key proteins in these pathways were then measured, as phosphorylation states are indicators of pathway activation or suppression. Additionally, the ...
In mice, a ketogenic diet remodeled the translatome of pancreatic cancer cells, rendering them vulnerable to targeted therapy ...
while pathways like adipogenesis, fatty acid metabolism, and oxidative phosphorylation were downregulated. Conversely, C2 exhibited the opposite trends in these pathways compared to C1. C3 showed ...
This process is regulated by FOXP1 O-GlcNAcylation, which represses its interaction with ATR, while CHK1-mediated phosphorylation of FOXP1 inhibits its O-GlcNAcylation upon replication stress.
1 Yulin Hospital, First Affiliated Hospital of Xi’an Jiao Tong University, Yulin, China 2 Department of Dermatology, Second Affiliated Hospital of Xi’an Jiao Tong University, Xi’an, China 3 Department ...
Encouragement in persecution; instruction concerning the day of the Lord; commandments to work. And to you who are troubled rest with us, when the Lord Jesus shall be revealed from heaven with His ...
The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in ...
Researchers investigate the influence of Mettl1 on energy metabolism and the maturation of heart cells after birth.