In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...

Pathway analyses of DEGs identified by RNA-seq ... RNA-seq and survival data are derived from the TCGA CESC cancer patients. (J/K) AKT and ERK phosphorylation is partially regulated by MCAM and IGFBP3 ...

The changes in phosphorylation states of key proteins in these pathways were then measured, as phosphorylation states are indicators of pathway activation or suppression. Additionally, the ...

while pathways like adipogenesis, fatty acid metabolism, and oxidative phosphorylation were downregulated. Conversely, C2 exhibited the opposite trends in these pathways compared to C1. C3 showed ...

In mice, a ketogenic diet remodeled the translatome of pancreatic cancer cells, rendering them vulnerable to targeted therapy ...

Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...

The true Church; reconciliation in Christ; warning against false teaching; Christian virtues. For this cause we . . . pray . . . that ye might be filled with the knowledge of His will in all wisdom ...

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in ...

Researchers investigate the influence of Mettl1 on energy metabolism and the maturation of heart cells after birth.

NYU Grossman School of Medicine is a founding member of the Consortium of Accelerated Medical Pathway Programs (CAMPP). Formed in 2015 with eight medical schools and funded by the Josiah Macy Jr.

Dec. 6, 2024 — Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging ...