Two-year data with eyeDNA Therapeutics’ gene therapy for retinitis pigmentosa (RP), an inherited form of blindness, has prompted the biotech to seek discussions with regulators about the design ...

在包括人类在内的许多物种中，群居生活能够提高生存率。与此相反，社交隔离会产生一种令人厌恶的状态（即“孤独感”），这种状态会促发对社交的渴望，并在重新团聚时增强社交互动。由社交隔离所引发的、可观察到的社交互动反弹现象表明，在对社交需求的控制背后，存在着一种稳态调节过程，这类似于饥饿、口渴或睡眠等生理驱 ...

The University of Bristol research team used animal models to compare patient responses to AAV therapy, studying male and female eye cells across different age groups (young, middle-aged and older ...

研究人员针对视网膜色素变性（RP）开展 PEDF 衍生肽研究，发现 H105A 肽滴眼液可促进光感受器存活，具有治疗潜力。 视网膜退行性疾病，如视网膜色素变性（Retinitis Pigmentosa，RP）和年龄相关性黄斑变性（Age - related Macular Degeneration，AMD），正逐渐成为导致失明的 ...

LUXTURNA has significant market potential due to the high unmet need for effective treatments in rare genetic conditions. With its FDA approval for specific mutations in the RPE65 gene, it offers ...