pRb 是一种重要的肿瘤抑制蛋白，正常情况下，pRb 与转录因子 E2F 结合，抑制细胞周期相关基因的转录，阻止细胞进入 S 期 。HPV E7 蛋白（49 - 57）片段能够与 pRb 结合，干扰 pRb - E2F 复合物的形成，释放 E2F，从而激活细胞周期相关基因的转录，促进细胞增殖 ...

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The Public Rental Board has received over 200 applications seeking an affordable housing opportunity. It says these applications are from the first three months of this year. General Manager Timoci ...

MiR-146b has been identified as being overexpressed in human bladder cancer (BCa) and implicated in promoting cancer cell invasion. However, its specific involvement in BCa cell growth remains unclear ...

"I've learned a lot of lessons and I've made mistakes and I just want this to be right," the singer said Marina Watts is a Digital Writer, Music at PEOPLE. She has been working at PEOPLE since ...

With so much of the spotlight on new fads every other week, from glass skin to glazed donut skin, we overlook the basic essential for healthy skin: protecting the skin barrier. No skin is entirely ...