Cash and cash receivable balance of $20.9 million as of December 31, 2024, expected to fund operations, including clinical activities ...

New data on Lynparza (olaparib), as well as PARP drugs from Pfizer and Johnson ... as would be expected given the drug’s mechanism. Despite the miss, AZ and Merck insisted the data reinforced ...

Cash and cash receivable balance of $20.9 million as of December 31, 2024, expected to fund operations, including clinical activities into 2027Strengthened cash position expected to support ...

"What's interesting is that drugs targeting these processes are already in use," Pruneda said. "PARP inhibitors, for example, are being used in the clinic, and now we're starting to appreciate the ...

AstraZeneca has become the first company to get approval for the combination of an immunotherapy with a PARP inhibitor for treating endometrial cancer. The European Commission has cleared AZ's PD ...

Now, PARP inhibitors work by stopping the repair mechanism. So when there is DNA damage caused as a result of killing off cancer cells, PARP inhibitors stop the ability of the cancer cell to ...

Small molecules are low molecular weight molecules that include lipids, monosaccharides, second messengers, other natural products and metabolites, as well as drugs and other xenobiotics. They are ...

Lantern Pharma Inc. , a clinical-stage biopharmaceutical company leveraging its proprietary RADR® artificial intelligence (AI) and machine learning (ML) platform to transform the cost, pace, and ...

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis, for instance by involving a combination of several different types of catalysis. Determining enzyme ...