For advanced purification, all proteins were passed through a Superdex S-75 column (GE Healthcare) with buffer A. The molecular mass of all four proteins was estimated in buffer A using a Superdex ...

纯合突变导致多种分子病理变化：26 - 27 个月大的纯合突变小鼠的 SN TH 神经元中，tau 磷酸化水平升高、脂褐素积累增加、自噬体标记蛋白 p62 表达增多、溶酶体相关膜蛋白 1（LAMP1）表达降低，同时还存在氧化损伤和脂质过氧化增强的现象，且谷胱甘肽过氧化物酶 ...

Muscle proteins of the obscurin protein family play important roles in sarcomere organization and sarcoplasmic reticulum and T-tubule architecture and function. However, their precise molecular ...

The structural and functional integrity of glomerular cells is critical for maintaining normal kidney function. Glomerular diseases, which involve chronic histological damage to the kidney, are ...

Install via my repository to ensure all module dependencies are up to date.

Pathological cardiac hypertrophy is the abnormal enlargement of the heart muscle in response to chronic stressors such as hypertension, myocardial infarction, or valvular disease. This maladaptive ...

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