Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically ... FdAT2 organoids ...

The HUMANOID Center at UC San Diego is pioneering organoid research aimed at improving the reliability and reproducibility of ...

Moreover, we performed drug screening tests to evaluate the effects of chemotherapeutic drugs and targeted drugs. Conclusion: The sigmoid colon cancer organoid with spinal metastases was a favorable ...

This field of research is crucial for both basic and translational research due to cardiovascular disease being the leading cause of death in the developed world. Additionally, drug-associated ...

27, 2025 — Heart disease remains the leading cause of death ... Cell-Based Therapy Improves Outcomes in a Pig Model of Heart Attacks Jan. 7, 2025 — In a large-animal model study, researchers ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

The company finally unveiled the new system in September, outing it as OpenAI’s first “reasoning” model and renaming it “o1.” Much like the two-stage release of GPT-2, where a stripped ...

scRNA-seq revealed dysplastic cells arise directly from mutant progenitors rather than progressing through metaplasia. In vitro, p53 mutation enhanced BE progenitors’ organoid-forming efficiency, ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

Physician–scientists at the University of Utah's John A. Moran Eye Center have published an investigatory review of nine patients who experienced vision complications while taking popular ...