Newer antipsychotics, such as clozapine, olanzapine, risperidone, quetiapine and ziprasidone, have a different receptor-binding profile, interacting with both D and 5-HT receptors; they less ...
The ABCB1 transporter gene The 2677(T) variant of the ABCB1 gene holds promise as a biomarker for adjusting dosing for olanzapine and clozapine. The DRD3 (Ser9Gly) polymorphism, could prove useful ...
For around 70 years, the treatment of schizophrenia has relied almost entirely on drugs that block dopamine receptors ... with dopamine-acting drugs like olanzapine and risperidone, such as ...
Spravato is the first ketamine-based medicine approved to treat depression, and also the first of a new class of glutamate NMDA receptor-targeting drugs that have ended a decades-long drought at ...