The conformational changes observed near the iron-molybdenum cofactor were directly linked to the state of nucleotide hydrolysis, providing a clearer picture of how energy is transduced during ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Hunan Joint International Research Center for Carbon Dioxide Resource Utilization, School of Physics, Central South University, Changsha 410083, Hunan, P. R. China School of Metallurgy and Environment ...

Celery, a key vegetable in the Apiaceae family, is widely valued for its nutrition and medicinal uses. It is commonly categorized into three varieties: A. graveolens var. dulce (common celery ...

KEGG pathway network analysis of 108 ubiquitinated proteins identified four statistically significant signaling pathways, including PI3K-AKT signaling pathway, hippo signaling pathway, ribosome, and ...

Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269, United States ...

aCentre for Rheumatology Research, Department of Medicine, University College London, Rayne Building, London W1CE 6JF, UK bCentre for Adolescent Rheumatology Versus Arthritis, Department of Medicine, ...

There is no rise in lactate due to complete failure of glycogen breakdown in muscles. An increased reliance on purine nucleotide metabolism (via myoadenylate deaminase) and phosphocreatine hydrolysis ...

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada Methods: To ...

This useful study introduces the peptidisc-TPP approach as a promising solution to challenges in membrane proteomics, enabling thermal proteome profiling in a detergent-free system. While the concept ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...