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综述:哺乳动物雷帕霉素靶蛋白(mTOR)通路在乳腺癌干细胞(BCSCs ...
BCSCs 通过 Notch3/mTOR 轴抑制 PD-L1 表达,逃避免疫监视;HIF-1α 和 HIF-2α 通过激活 mTOR 信号通路,促进 BCSCs 特性和肿瘤进展;ST8SIA1 调节 BCSCs 功能,与肿瘤进展相关;SALL1 作为肿瘤抑制因子,通过调节 mTOR 信号通路抑制乳腺癌细胞生长;PROCR 激活多种信号通路 ...
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