We demonstrate that decidual γδT cell subsets, including Vδ1, Vδ2, and double-negative (DN) Vδ1-/Vδ2- cells express HLA-specific regulatory receptors, such as NKG2C, NKG2A, ILT2, and KIR2DL4, each ...

NKG2 members form a heterodimer with CD94 and recognize HLA-E. NKG2A/CD94 is an inhibitory receptor owning ITIM in their cytoplasmic. While, NKG2C/E is activating receptors associated with the DAP12.

Results NKp46 (but not CD94, NKG2A, NKG2C, NKG2D) was significantly more expressed by malignant RCDII IEL than by normal IEL in CD and RCDI. In paraffin biopsies, detection of >25 NKp46+ IEL per 100 ...