Atopic dermatitis (AD) is a chronic inflammatory skin disease with high prevalence, especially in children. Current ...

Juvenile dermatomyositis (JDM) is a rare autoimmune condition with insufficient biomarkers and treatments, in part, due to incomplete knowledge of the cell types mediating disease. We investigated ...

本文发现 SPARCL1 可促进肺泡 2 型（AT2）细胞分化，揭示其在肺发育中的重要作用及潜在应用价值。 ### 肺泡发育研究背景 在小鼠胚胎发育晚期（E16 - E18），胎儿肺会经历显著的形态发生转变，肺泡上皮祖细胞也会分化为不同的呼吸细胞类型，其中肺泡 2 型（AT2 ...

Objective The Collaborative Cross (CC) is a mouse population model with diverse and reproducible genetic backgrounds used to identify novel disease models and genes that contribute to human disease.