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5 天
线粒体自噬相关基因在骨肉瘤中的研究:发现预后基因并构建风险模型
线粒体自噬(Mitochondrial autophagy)是细胞内清除受损线粒体、维持细胞稳态的关键过程,与多种癌症密切相关,在肿瘤发生发展中扮演着复杂角色,既能抑制肿瘤,也可能促进肿瘤进展。在骨肉瘤领域,线粒体自噬相关基因(Mitochondrial autophagy related genes,MARGs)的预后作用及生物学功能却知之甚少,缺乏可靠的 MARGs ...
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