和 细胞毒性微管抑制剂（MMAE，单甲基奥瑞斯他汀E）通过 MC-Vc-PAB 连接子 偶联而成。 Cetuximab-MMAE 通过以下机制发挥其抗肿瘤作用： 靶向作用：Cetuximab 精确地靶向表达 EGFR 的肿瘤细胞，通过结合 EGFR，阻断其下游信号通路，抑制肿瘤细胞的增殖。 药物释放 ...

Background The aim of this study was to evaluate the preliminary experience of a combined middle meningeal artery embolization (MMAE) and burr hole evacuation approach for chronic subdural hematoma ...

Alexa Fluor 488 Cholera Toxin Subunit B是一种高效的荧光标记试剂，由霍乱毒素B亚基（CTB）与Alexa Fluor 488荧光染料偶联而成。Alexa Fluor 488 CTB具有亮绿色的荧光，激发波长为488nm，发射波长为519nm，适用于多种荧光显微镜和流式细胞仪。它利用CTB与细胞膜上神经节苷脂GM1的 ...

FOR46 (targeting CD 46), is a fully humanized ADC with MMAE payload. Phase 1 data shows promise ... Schweizer MT, Gulati R, Nelson PS, Haffner MC. ASSESSMENT OF CELL SURFACE TARGETS IN METASTATIC ...

What are the best Minecraft mods in 2025? Every game of vanilla Minecraft can vary quite dramatically, and the best Minecraft mods go one step further to provide an entirely new experience.

The second ADC, SGN-CD19A (Seattle Genetics), comprises a humanized anti-CD19 monoclonal antibody conjugated with MMAF using the noncleavable MC, which is the same linker–cytotoxic agent ...

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Knowing what the best Minecraft server hosting is really matters if you're an avid Minecraft fan who is keen to manage their own server on a regular basis. That could be if you plan on hosting a ...