为探究 MAP4K4 在糖尿病视网膜病变中的作用，研究人员开展研究，发现其关键作用及潜在治疗策略。 在糖尿病视网膜病变这类视网膜微血管病变中，调节内皮细胞（EC）功能障碍、缺血和炎症的信号通路起着至关重要的作用。丝裂原活化蛋白激酶激酶激酶激酶 4 ...

Combined, these findings show that CMA displays a broad targetability on multiple steps of the EMT process and indicate a substantial role of CMA in regulating the stability of pro-metastatic and ...

Introduction: Among the various stromal cell types within the tumor microenvironment, cancer-associated fibroblasts (CAFs) emerge as the predominant constituent, exhibiting a diverse array of ...

2 Beijing Key Laboratory for Genetic Research of Skeletal Deformity, Beijing, China Background Brain arteriovenous malformations (BAVM) represent a congenital anomaly of the cerebral vessels with a ...

© 2025 American Heart Association, Inc. Departments of Surgery (T.M.B., J.M., J.S., S.B., K.A.G.), University of Michigan, Ann Arbor. Departments of Surgery (T.M.B ...