编辑推荐：本研究针对胃癌转移过程中循环肿瘤细胞(CTCs)存活率低的难题，创新性建立CTC-PBMC共培养系统，成功培育4株长期 ...

肿瘤 FOLR1 表达代表 HCC 预后不良的分子亚型，具有侵袭性生物学特征：对高 FOLR1 表达的 HCC 患者分子特征进行研究发现，FOLR1 表达与预后不良的分子亚型相关，且高 FOLR1 表达亚组中与 HCC 干细胞特征相关的通路以及多种致癌通路（如 p53、DNA 修复、Myc、E2F 和 PI3K ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

The management of retinoblastoma, the most common intraocular malignancy in children, has changed drastically over the last decade. Landmark developments in local drug delivery, namely, safer ...

GSEA analysis showed that the high expression group of KIF18B was mainly enriched in E2F, G2M and other signaling pathways. The results of immunoassay showed that the expression of KIF18B was ...

1Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts. 2Department of Mathematics, University of Massachusetts Boston, Boston, Massachusetts.

Interestingly, Rb-E2F targets like BRCA1 were also found to be regulated through the “non-canonical” DREAM pathway via p53-E2F4 co-recruitment (Bindra and Glazer, 2006). Perhaps having greater ...

Background and aims Alcohol-associated hepatitis (AH) is an acute form of alcohol-related liver disease (ALD) with high mortality rate. AH is histologically characterised by cellular processes, ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

2025-03-08 18:00发布于北京奇点网官方账号 *仅供医学专业人士阅读参考 作为一种重要的基因调控机制，RNA编辑在肿瘤研究领域的出场率越来越高。