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12 小时
ALKBH5 介导的 m6A 调控卵巢癌中 SRSF10 可变剪接事件:开启卵巢癌治疗 ...
为探究 m 6 A 去甲基酶 ALKBH5 影响卵巢癌(OC)RNA 剪接的机制,研究人员开展相关研究。发现 OC 患者中 ALKBH5 高表达、m 6 A 水平降低,敲低 ALKBH5 可抑制癌细胞活力等,且明确 SRSF10 是关键靶点。该研究为 OC 的 m 6 A 修饰治疗提供新思路。
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