Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...

1 School of Computer and Information Engineering, Luoyang Institute of Science and Technology, Luoyang, China 2 State Key Laboratory of Bioelectronics; School of Biological Science & Medical ...

Background: The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). Despite the critical role of natural killer ...

本研究聚焦于儿科脓毒症，通过对比脓毒症患者、健康对照及普通感染患者的血浆肽组学特征，揭示了脓毒症相关的差异表达肽段，为早期诊断和治疗提供了新思路。 脓毒症是一种由感染引起的失调性免疫反应，严重时会导致多器官功能障碍，尤其在儿童中发病 ...

This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

In this valuable study, the authors aimed to identify and characterize intrinsic factors that govern the aging process of bone marrow mesenchymal stromal cells (BMSCs), which are believed to be ...