前言既往研究证实钠-葡萄糖协同转运蛋白2抑制剂（SGLT2i）对成人慢性肾脏病（CKD）、2型糖尿病（T2DM）、慢性心力衰竭（HF）有良好的治疗作用。不仅如此，近期发表在柳叶刀子刊《EBioMedicine》的一项研究表明，SGLT2i还可以降低糖 ...

为探究 ATP6AP1 在管腔型乳腺癌中的作用，南昌大学等研究人员开展相关研究，发现其促进细胞增殖和他莫昔芬耐药，有重要意义。

2023). In addition to the cytotoxic effects of Cu in neurons, Cu-induced microglial activation is also at least partially mediated by mitochondrial membrane damage and impaired mitophagy evidenced by ...

Previous studies have reported that disruption of the M2 LIR motif reduces LC3B lipidation during infection (Beale et al, 2014). To analyze the role of M2 cleavage, we assessed LC3B lipidation induced ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipid transfer proteins mediate the ...

Similarly, LC3B and p62, markers of autophagy, indicated no induction of autophagy in testicular tissue following anti-PD-1 treatment. Furthermore, NLRP3 expression did not significantly differ ...

Division of Multi-Organ Transplantation, Department of Surgery, University of California, San Francisco, United States; Bakar Computational Health Sciences Institute, University of California, San ...

Research in my group focusses on the mechanism of action of mycolactone, the lipid-like exotoxin of the Buruli ulcer infectious agent, Mycobacterium ulcerans. Mycolactone has many unusual and ...