该研究成果发表在《The Journal of Membrane Biology》上。 在研究过程中，研究人员主要运用了以下关键技术方法：一是分子动力学模拟，将大鼠胰腺的 Kir6.2（KATP?通道的主要组成部分）与 ATP 结合或不结合的状态，嵌入不同胆固醇浓度的 1,2 - 二棕榈酰磷脂酰胆碱（DPPC ...

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Gestational diabetes is a major public health problem because of its prevalence, its associated complications during pregnancy, and its increased risk for type 2 diabetes later in life.

Scientists have long recognized the brain's need for energy, but new research from the University of Kentucky's Sanders-Brown ...

为探究赖氨酸 2 - 羟基异丁酰化（Khib）在房颤（AF）中的作用，研究人员经多实验发现其影响能量代谢和 K ATP 通道功能，为 AF 研究提供新视角。 心房颤动（Atrial Fibrillation，AF）是临床上最为常见的心律失常病症，它就像一颗隐藏在心脏里的 “定时炸弹”，随时 ...

Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, United States Department of Medical Biochemistry, College of Medicine, Tanta University, Tanta, Egypt ...

Nintendo Switch 2 is finally confirmed. After literal years of unverified rumors, dubious leaks and copious amounts of online speculation, Nintendo has lifted the lid on its next-generation ...

The Ark 2 trailer that dropped at E3 2022 though is captured in Unreal Engine 5 and looks utterly stunning. Although it's not gameplay, it sets the tone for the game's storyline, which takes place ...

Partial solar eclipse: Where and when ...

Death Stranding 2 is coming our way, with the official reveal of a June release date confirming we won't have to wait much longer to step into the adventure for ourselves. Officially called Death ...

Kir6.2-K ATP channels are expressed on excitatory and inhibitory neurons within the mouse brain. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2416578122 ...