Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Researchers found that while sweat biomarkers remain stable, plasma biomarkers show significant inflammatory changes after a ...

Data Generated to Date Support Potential for Aclaris’ ATI-2138 to Impact Several Human Inflammatory Diseases - WAYNE, Pa., ...

SignalChem Biotech, part of Sino Biological, offers one of the largest active enzyme collections in the world and specializes ...

In this video, Aruna Padmanabhan, MD, discusses the effectiveness of cyclin-dependent kinase inhibitors in the treatment of metastatic hormone-positive breast cancer.

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

American Society of Clinical Oncology Genitourinary (ASCO GU) cancers symposium held in San Francisco, CA between February 13 th and 15 th 2025, was host to the Panning for Gold: The Role of ctDNA as ...

为解决膀胱癌治疗中 BCG 疗效不佳的问题，石河子大学医学院的研究人员开展了 Mcl-1 下调联合 BCG 治疗膀胱癌的研究。结果显示该联合治疗可促进巨噬细胞极化，提升疗效。这为膀胱癌治疗提供新思路，强烈推荐科研读者阅读。

Detecting toxic forms of tau before they weave into dense thickets of tangles could pave the way for earlier diagnosis and ...

为解决肾癌预后评估和治疗难题，首都医科大学研究人员开展 MAGI3 相关研究。发现 MAGI3 可影响肾癌对舒尼替尼敏感性且是预后标志物。该研究为肾癌精准治疗提供新思路，强烈推荐科研读者阅读。

A CRISPR-based system that erases itself from fly populations may offer a safer approach to tackling insecticide resistance while minimizing ecological risks.