Many of the cells in our bodies are quiescent, that is, temporarily not dividing. Under certain physiological conditions such as during tissue repair and maintenance, quiescent cells receive the ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

我们提供FLAG标签的组蛋白甲基转移酶（HMTs）、组蛋白去甲基化酶（HDMs）、蛋白质精氨酸甲基转移酶（PRMTs）、PRDMs以及多种酶复合物，覆盖包括NSD2、DOT1L、LSD1、KDM5A、KDM5B和PRC2在内的多个药物靶点。 Active Motif是一家全球领先的生命技术公司，专注于表观遗传学 ...

The basic building blocks of chromatin are nucleosomes, each of which is composed of 146 bp of DNA wrapped around a histone octamer that consists of two copies each of H2A, H2B, H3 and H4.

Cardiac fibrosis, a hallmark of heart failure and various cardiomyopathies, represents a complex pathological process that has long challenged therapeutic intervention. High-throughput omics ...