试验的主要结局是 3 个月后的健康状况,通过堪萨斯城心肌病问卷总体总结评分(KCCQ-OSS)评估。次要结局包括口渴不适和安全事件。在 504 名随机分组的患者(男性占 67.3%)中,自由液体摄入组 3 个月后的 KCCQ-OSS 为 74.0,液体限制组为 72.2,经基线评分调整后的 ...
Additionally, patients under age 70 in the MIH group showed more improvement in health status than those in the TOCC group, where younger patients saw less gain on KCCQ scores than older adults.
Patients showed similar changes in their Kansas City Cardiomyopathy Questionnaire (KCCQ) Overall Summary Scores 3 months into the trial whether they had been allowed liberal fluid intake or told ...
The majority of participants (87.1%) had NYHA class II symptoms, and most were taking standard HF medication; 51% were taking loop diuretics. Their median baseline KCCQ Overall Summary Score (KCCQ-OSS ...
Lilly's drug also significantly improved heart failure symptoms and physical limitations measured using the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) compared to ...
The primary outcome was health status at 3 months as assessed by Kansas City Cardiomyopathy Questionnaire overall summary score (KCCQ-OSS) adjusted for baseline values with analysis of covariance.
Total number of enrollees: 504 Duration of follow-up: 3 months Mean patient age: 69.2 years Percentage female: 32.7% The primary outcome, the Kansas City Cardiomyopathy Questionnaire-Overall Summary ...
Statistically significant and clinically meaningful improvements in heart failure-related health status, measured by the Kansas City Cardiomyopathy Questionnaire-Clinical Summary Score (KCCQ-CSS ...
The study’s two primary endpoints, assessed at 30 days, were all-cause hospital readmission and change in overall summary score on the Kansas City Cardiomyopathy Questionnaire (KCCQ), which measures ...