Ninerafaxstat improves cardiac energetics, cardiac reserve capacity, 6-minute walk distance and heartfailure-related health status (KCCQ) in ...

Edgewise Therapeutics, Inc., , a leading muscle disease biopharmaceutical company, today announced positive top-line data of EDG-7500 from the Phase 2 CIRRUS-HCM four-week trial in participants with ...

The SUMMIT trial enrolled obese patients with heart failure with preserved ejection fraction (HFpEF) – a particularly hard-to-treat form ... using the Kansas City Cardiomyopathy Questionnaire ...

People with heart failure have long been advised to limit the amount of fluids they consume each day to help reduce congestion, or the buildup of fluid in the lungs and extremities, but that advice ...

Participants taking tirzepatide also had a better average Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) than the placebo group, showing a significant improvement in ...

Statistically significant and clinically meaningful improvements in heart failure-related health status, measured by the Kansas City Cardiomyopathy Questionnaire-Clinical Summary Score (KCCQ-CSS ...

As its name suggests, the study enrolled patients with heart failure with preserved ejection fraction (HFpEF), a particularly hard-to-treat form ... on the Kansas City Cardiomyopathy Questionnaire ...

Additionally, patients under age 70 in the MIH group showed more improvement in health status than those in the TOCC group, where younger patients saw less gain on KCCQ scores than older adults.

The majority of participants (87.1%) had NYHA class II symptoms, and most were taking standard HF medication; 51% were taking loop diuretics. Their median baseline KCCQ Overall Summary Score (KCCQ-OSS ...

The primary outcome was health status at 3 months as assessed by Kansas City Cardiomyopathy Questionnaire overall summary score (KCCQ-OSS) adjusted for baseline values with analysis of covariance.

The drug tirzepatide improved kidney function and cardiovascular outcomes among patients with obesity and heart failure with ...