All studies were conducted in accordance with the local legislation and institutional requirements. Il23r floxed mice were kindly provided by Philip Rosenstiel. MC-38 cells were a gift from Dr.

Human microbial colonization begins at birth and continues to develop and modulate in species abundance for about 3 years, until the microbiota becomes adult-like. During the same time period, ...

通过 GWAS 分析，研究人员发现了 28 个与结节病相关的基因组位点。其中，C1orf141 - IL23R 基因附近的位点影响最大。每增加一个次要等位基因（C 等位基因），患结节病的几率就会增加 1.59 倍（95% 置信区间 1.45 - 1.75）。这一发现为理解结节病的遗传基础提供了关键 ...

Collaborative Innovation Center for Modern Grain Circulation and Safety, Jiangsu Province Engineering Research Center of Edible Fungus Preservation and Intensive Processing, College of Food Science ...

IL - 12/23 在人类中枢神经系统的转录调控：对人类中枢神经系统的转录组分析发现，神经元和少突胶质细胞表达 IL12RB1 和 IL12RB2 转录本，而 IL23R 表达较弱。这说明 IL - 12 信号通路在人类中枢神经系统中同样存在且可能发挥重要作用。 神经元和少突胶质细胞是 IL ...

Professor R C Trembath, Division of Genetics and Molecular Medicine, King’s College School of Medicine, 9th Floor Guy’s Tower, Guy’s Hospital, SE1 9RT London, UK; ...

1 Department of Medicine, Division of Gastroenterology & Hepatology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK 2 Wellcome Trust PhD Programme for Clinicians, Cambridge Institute ...

aMedical Clinic 1, Department of Gastroenterology, Ludwig Demling Endoscopy Center of Excellence, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany ...