Mathieu van der Poel decimates peloton across Flemish cobbles for repeat victory at E3 Saxo Classic / How it unfolded For a second year in a row, Mathieu van der Poel (Alpecin-Deceuninck ...
This evening will start with a few patches of cloud lingering. These will soon dissipate, resulting in clear skies through the rest of the night. A chilly night. Saturday Tomorrow morning will ...
The current review attempted to summarize the status quo of IAPs’ role in promoting chemotherapeutic drug resistance in various cancer treatments and discuss the most recent development of ...
推荐语:这篇综述系统阐述了X连锁凋亡抑制蛋白(XIAP)通过抑制caspases、激活核因子κB(NF-κB)等通路调控凋亡的双重途径(死亡受体与线粒体途径),其异常表达与肿瘤发生发展密切相关,为靶向治疗提供了新思路。 XIAP的结构与功能特性 X连锁凋亡抑制蛋白 ...
为探究 X 连锁凋亡抑制蛋白(XIAP)促进膀胱癌转移的机制及 YTHDC1 的上游调控机制,温州医科大学等研究人员开展 XIAP 相关研究。结果发现 XIAP 可泛素化 YTHDC1,促进 MMP-2 表达,推动膀胱癌转移,为膀胱癌治疗提供潜在靶点。