Loss-of-function changes in the histidine triad nucleotide-binding protein 1 (HINT1) are associated with autosomal recessive axonal neuropathy with neuromyotonia (NMAN [MIM: 137200]) (1), the symptoms ...

Methods High throughput screening of 170 000 compounds identified a small molecule gp130 modulator termed regulator of cartilage growth and differentiation (RCGD 423) that promotes atypical ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

Hepatitis C is inflammation of the liver in humans caused by the hepatitis C virus. The virus is primarily transmitted by blood-to-blood contact associated with transfusion and intravenous drug ...

A) Visual depiction of the RNA homodimer formation process: Inter-ligated fragments (arms) originating from homodimeric RNA molecules generate chimeras, where each arm aligns to overlapping ...

13 It is also binding to TNF-related apoptosis-inducing ligand (TRAIL), an important regulator of cell survival.14 15 STC1, a secreted, homodimeric glycoprotein that is expressed in a wide variety of ...