Heme degradation plays important biological roles, ranging from generating light-absorbing compounds in plants to facilitating iron homeostasis in mammals. The X-ray crystal structure of human ...

The following is a summary of “Novel protein C variant p.C101F results in early intracellular degradation that drives type I ...

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The FDA has granted AUTX-703, a first-in-class oral KAT2A/B degrader, fast track designation for the treatment of ...

Hematology oncology is a medical specialty concerned with diagnosing and treating blood, bone marrow, and lymphatic system cancers such as leukemia and lymphoma. It is sometimes also referred to as ...

The Food and Drug Administration granted fast track designation to AUTX-703 for relapsed or refractory acute myelogenous ...

Planning Activities Are Ongoing for Next Phase of Cemsidomide Clinical Development in Multiple Myeloma and Non-Hodgkin’s Lymphoma; Trials Expected to Initiate in Early 2026 CFT1946 Phase 1/2 Trial ...

Total global revenues of $1.1 billion and $3.8 billion for the fourth quarter and full year, increases of 78% and 55%, respectively; narrowed GAAP operating loss and achieved full-year positive ...

Rivian's R2 SUV, which is expected to challenge Tesla's Model Y, will launch early next year.

"In cancer progression, protease activation facilitates the degradation of the extracellular matrix and allows cancer cell invasion and dissemination, highlighting the potential of proteases as a ...