1Fred Hutch Cancer Center, Seattle, WA.

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BACKGROUND: Previous studies have shown that the anti-cholestatic effect of oleanolic acid (OA) is associated with FXR and NRF2. However, how the two signaling pathways cooperate to regulate the ...

We further elucidated that ApoA1 activated NRF2, the transcription factor of SLC7A11, by promoting its nuclear translocation. Conclusion: Our results imply that HDL/ApoA1 inhibits macrophage ...

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