McManus et al, NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression, Immunity (2025). DOI: 10.1016/j.immuni.2025.01.007 ...

“Glucose drives the glycolysis pathway, while glutamine drives the glutaminolysis pathway.” He added: “No tumor, including GBM, can survive without glucose and glutamine. Our study has identified a ...

A new study finds a ketogenic diet can improve bipolar disorder symptoms and reverse co-occurring metabolic syndrome. A ketogenic diet works on shared psychiatric and metabolic risk factors. Experts ...

Retinal pigment epithelial (RPE) cells form a monolayer between the neuroretina and choroid. It has multiple important functions, including acting as outer blood-retina barrier, maintaining the ...

Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies and ultimately leads to right heart failure as the predominant cause of morbidity and mortality. In patients, ...

Scientists from DZNE, University Hospital Bonn (UKB) and the University of Bonn provide new evidence that preventing brain inflammation is a promising approach for the treatment of Alzheimer's ...

This study reveals that PRMT1 overexpression drives tumorigenesis of acute megakaryocytic leukemia (AMKL) and that targeting PRMT1 is a viable approach for treating AMKL. While the evidence, based ...

Department of Pediatrics, Pediatric Intensive Care Unit, Shengjing Hospital of China Medical University, Shenyang (N.Y., Y.-P.L., R.W., Y.-H.Y., T.Z., X.-R.Y., Y.-F.X ...

Cardiovascular diseases (CVDs) are experiencing a rapid surge and are widely recognized as the leading cause of mortality in the current aging society. Given the multifactorial etiology of CVDs, ...