Most psychiatric disorders are highly heritable, yet few reproducible genetic risk factors have been identified by linkage analysis and candidate gene or genome-wide association studies.

Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the global disease burden, contributes substantially to societal and economic costs, and leads to approximately 3 ...

This important study has modified ChIP-seq and 4C-seq procedures with a urea step and shows that this drastically changes the pattern of chromatin interactions observed for SATB1 but not other ...

Identification of BURs as direct targets of SATB1 in vivo by urea ChIP-seq. A) Contrasting distributions of SATB1-binding profiles determined by urea ChIP-seq (Urea) compared to standard ChIP-seq (Std ...