DNA polymerases carry out crucial functions in many DNA metabolic processes. Polymerases catalyse the addition, using a template, of complementary nucleotides to the 3′ end of DNA primer strands.

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

As the replication of genomic DNA is arguably the most important task performed by a cell and given that it is controlled at the initiation stage, the events that occur at the replication origin play ...

A recent review highlights the critical role of DNA exonucleases and endonucleases in immune response and disease management, shedding new light on ...

This month's cover highlights the article Organotypic culture of human brain explants as a preclinical model for AI-driven antiviral studies by Emma Partiot, Barbara Gorda, Raphael Gaudin and ...

Following this, an exonuclease removes the damaged area, followed by DNA polymerase resynthesis and DNA ligase nick sealing ... When complicated lesions are repaired and when replication forks are ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.

Retraction of 'COUP-TF interacting protein 2 represses the initial phase of HIV-1 gene transcription in human microglial cells'.

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

A new study in the journal Nature throws a new theory into the fray. Analyzing a wealth of DNA collected from fossilized human bones, the researchers found that the first Indo-European speakers ...

The breakthrough came from DNA extracted from a bloodstained shawl found on victim Catherine Eddowes' body in 1888. Edwards purchased the historic shawl at auction in 2007. Working with genealogists, ...