SILAB presents new efficacy studies on LONGEVICELL, a natural anti-aging active ingredient obtained from myrtle leaves and targeting sirtuins and their coactivators (NAD + and AMPK) ...

AMPK and its downstream target, mTOR, serve as central hubs to nutrient availability ... Sirtuin-1 (SIRT1) serves as another crucial energy sensor. It is activated by NAD+ in nutrient-deficient states ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

This review highlights the relationship between myokines and AMPK as an established mediator of the functional and metabolic effects of exercise on skeletal muscle. Of those myokines, IL-6, IL-8, and ...

Feb. 7, 2025 — An expert in energy technologies uses AI tools to investigate the impact of extreme weather on solar-powered and electrified homes and uncover their ... New Record for CIGS ...

Here, we found that inhibition of AMPK occurs during naïve transition with two conventional inhibitors of the MEK1 and GSK3β pathways. The accumulation of glycogen due to iGSK3β is responsible for ...

Feb. 21, 2025 — Perovskite solar cells are highly efficient and low cost in production. However, they still lack stability over the decades under real weather conditions. An international ...

February 13, 2025 • Panama has been looking for solutions to a long-term problem. Every time a ship passes through the Panama Canal, more than 50 million gallons of fresh water from Lake Gatun ...

AMPK is a heterotrimeric protein complex consisting of 3 subunits, α, β, and γ, each encoded by distinct genes. These isoforms play specific roles in AMPK stability and activity, and all 3 are ...

The logo of British multinational oil and gas company Shell is displayed during the LNG 2023 energy trade show in Vancouver, British Columbia, Canada, July 12, 2023. REUTERS/Chris Helgren/File ...