Here we review current knowledge of the roles of lipid metabolism and function in the CNS and discuss how modulating these pathways may offer novel therapeutic options for treating ALS. Lipids are ...

If lipid metabolism is dysregulated in adipocytes due to environmental or genetic factors, adipose tissue immunity and whole body energy metabolism are distorted. It has been suggested that endogenous ...

"Dyslipidemia" refers to an abnormality within the lipid profile, encompassing a variety of disorders relating to elevations in total cholesterol, LDL, or TG, or conversely, lower levels of HDL.

and via hexosamine metabolism under supraphysiological glucose concentrations, we hypothesize that chronic oxidative stress is an important mechanism for glucose toxicity. Support for this ...